Call for Nominations, ACS Fellows |
The TOXI Division gets to nominate four individuals each year for the prestigious ACS Fellows Award. This award takes into account Scientific Excellence and Service to Chemistry.
Eligibility. Nominees must be current members in good standing with ACS.
The selection of ACS Fellows is based on demonstrated contributions in two defined areas:
- Excellence in Science/Profession Could include, but is not limited to:
- Excellence in R&D
- Teaching or education
- Demonstrated leadership or managerial excellence in an organization within the chemical sciences
- Outstanding Service to the American Chemical Society Could include, but is not limited to:
- Governance service on a divisional, local, regional and/or national level
- Publications, such as editor, assistant or associate editor
- Meetings through organization of symposia or major presentations
- Involvement in National Chemistry Week, Chemists Celebrate Earth Day, and similar outreach activities
- Public communication by press, radio, TV or electronic media
Please send nominations to Frederick.Beland@fda.hhs.gov by Friday February 24, 2012. | Results from the Elections |
We have the winners of our 2011 Elections.
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Yinsheng Wang will be the new Treasurer-Elect. He is Professor of Chemistry at the University of California, Riverside. His research group uses mass spectrometry to probe DNA damage induced by reactive oxygen species and the post translational midification of proteins. |
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Gunnar Boysen will be our new Secretary. He is an Assistant Professor in the Department of Environmental and Occupational Health at the University of Arkansas. He is interested in the interplay between chemical exposure and nutritional or lifestyle habits, such as diet selection and physical activity. |
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Larry Wienkers is our new Member-at-Large on the Executive Council. Larry's current research interests focus on exploring bioactivation pathways associated with small-molecule drug metabolism, with particular focus on the prospective application of this information to predict drug-drug interactions in the clinic. |
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Peter Dedon will be on the Nominating Committee. Pete is Professor of Toxicology and Biological Engineering at MIT. His research group seeks to understand the chemical etiology of human disease, with the long-term goals of developing diagnostic tools and therapies. |
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| Call for Abstracts: ACS National Meeting and Exposition | The 244th American Chemical Society National Meeting and Exposition will take place in Philadelphia, Pennsylvania, August 19-23, 2012. The program theme is "Materials for Health and Medicine," and preliminary programming for the Division of Chemical Toxicology includes sessions on engineered nanomaterials, genome instability, and drug safety. Any programmatic questions may be directed to the program chair, Professor Shana J. Sturla at shana.sturla@hest.ethz.ch
On January 23, 2012, PACS, the online abstract submission system of the ACS, will open for author abstract submission for the ACS meeting. We encourage submissions for oral and poster presentations from investigators at all levels. Please access PACS via the meeting pages at www.acs.org. | Chemical Research in Toxicology |
Chemical Research in Toxicology brings you the latest developments in the chemical basis of toxicological responses. The journal publishes cutting edge research on the
- metabolism of toxic agents
- identification of novel toxic agents and reactive intermediates
- characterization of the interactions of toxic agents with cellular macromolecules
- biochemical and cellular responses to toxic assult.
| Chemical Carcinogen Reference Standards Synthesis Program |
The National Cancer Institute and Division of Cancer Biology announce the formation of the Chemical Carcinogen Reference Standards Synthesis Program, which can provide difficult-to-obtain chemicals for NIH- and NCI-supported researchers. This program replaces the Chemical Carcinogen Reference Standards Repository that was available through the Midwest Research Institute.
Eligibility: Requests will only be accepted from investigators with current NIH funding. Requested chemicals must be related to research described in the Specific Aims of an NIH grant with current active funding. Requests will not be accepted from investigators funded from other non-NIH sources, or from foreign grantees.
Application Format and Submission: Requests for chemicals may be submitted at any time and should be submitted electronically in MS Word or PDF format. Requests should be no more than two pages in length, including references. The application should contain the following information:
- The chemical to be synthesized (from the list of 70 compounds on the table below) and the quantity required. Requested quantities should be limited to that which is appropriate for the work proposed in the funding period of the associated grant.
- A description of how the chemical is to be used, and how this use is related to an existing NIH grant. Grants should be identified by Grant Number.
- A justification of why the chemical is needed, and why it cannot be obtained from other sources.
Requests must be countersigned by the requestor's Grants Administrative Official. They should be sent via email to Program Officer Ellen Zaika at zaikae@mail.nih.gov
Review: Requests for chemicals will be reviewed by NCI/DCB Program staff as they are received. Priority will be given in the following order: 1) DCB-funded grantees, 2) NCI-funded grantees, and 3) other NIH IC-funded grantees. Requests will be ranked on the basis of the need of the requested chemical for completion of the Aims of the funded grant, significance of the research utilizing the chemical, and programmatic considerations of the Cancer Etiology Branch, the DCB, and the NCI. Requests will be filled in rank order, based on the availability of funds.
Requestors will be notified by NCI or the contractor when synthesis of the requested chemical is initiated, with an estimate of when the chemical will be shipped. Requests will remain active for three additional review cycles. If requests are not selected for synthesis within that time, they will be discarded and the requestor will need to submit a new application.
Reports: Recipients of the compounds from the DCB Repository are required to acknowledge the support of the Repository whenever publicizing the work resulting from these NCI-supplied compounds in any media by including an acknowledgement statement essentially as follows: "This project was performed in part using compound(s) provided by the NCI operated under contract by The Pennsylvania State University, College of Medicine HHSSN261200900026C."
Within 1 year, applicants receiving compounds should submit a report electronically (to zaikae@mail.nih.gov) indicating how compounds were used and the scientific results obtained. Links to publications resulting from the use of the chemicals provided should be included in the report. Failure to provide a report may result in future requests being denied.
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List of Chemicals available from the Chemical Carcinogen Reference Standards Synthesis Program
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Chemical |
PSU # |
NCI# |
| 1 |
Benzo[a]pyrene |
101 |
G0074 |
| 2 |
1-Hydroxybenzo[a]pyrene |
102 |
L0100 |
| 3 |
3-Hydroxybenzo[a]pyrene |
103 |
L0075 |
| 4 |
7-Hydroxybenzo[a]pyrene |
104 |
L0105 |
| 5 |
9-Hydroxybenzo[a]pyrene |
105 |
L0106 |
| 6 |
Benzo(a)pyrene-trans-7,8-dihydrodiol(+/-) |
106 |
L0113 |
| 7 |
Benzo(a)pyrene-trans-9,10-dihydrodiol |
107 |
L0114 |
| 8 |
Benzo(a)pyrene-trans-7,8-dihydrodiol (-) |
108 |
O0468 |
| 9 |
Benzo(a)pyrene-trans-7,8-dihydrodiol (+) |
109 |
O0473 |
| 10 |
Benzo(a)pyrene-r-7,t-8,t-9,t-10-tetrahydrotetrol(+/-) |
110 |
L0618 |
| 11 |
Benzo(a)pyrene-r-7,t-8,t-9,c-10-tetrahydrotetrol(+/-) |
111 |
L0619 |
| 12 |
Benzo(a)pyrene-r-7,t-8,c-9,t-10-tetrahydrotetrol(+/-) |
112 |
L0629 |
| 13 |
Benzo(a)pyrene-4,5-dihydroepoxide(+/-) |
113 |
L0115 |
| 14 |
Benzo(a)pyrene-r-7,t-8-dihydrodiol-t-9,10-epoxide(+/-) (anti) |
114 |
L0137 |
| 15 |
Benzo(a)pyrene-r-7,t-8-dihydrodiol-c-9,10-epoxide(+/-) (syn) |
115 |
L0152 |
| 16 |
Benzo(a)pyrene-1,6-dione |
116 |
L0109 |
| 17 |
Benzo(a)pyrene-3,6-dione |
117 |
L0110 |
| 18 |
Benzo(a)pyrene-6,12-dione |
118 |
L0111 |
| 19 |
Benzo(a)pyrene-7,8-dione |
119 |
L0288 |
| 20 |
Benzo(a)pyrene-r-7,t-8,c-9,c-10-tetrahydrotetrol(+/-) |
120 |
L0621 |
| 21 |
Benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide (anti) (+) |
121 |
P0702 |
| 22 |
Benzo(a)pyrene-7,8-dihydroepoxide(+/-) |
122 |
L0622 |
| 23 |
Benzo(a)pyrene-trans-4,5-dihydrodiol(+/-) |
123 |
L0129 |
| 24 |
3-Benzo(a)pyrenyl-B-D-glucopyranosiduronic acid |
124 |
K0343 |
| 25 |
7R,8S,9S-Trihydroxy-10S-(N2-deoxyguanosyl-3'-phosphate)-7,8,9,10-tetrahydrobenzo[a]pyrene |
125 |
AD0884 |
|
| 26 |
1-Hydroxybenz(a)anthracene |
126 |
L0191 |
| 27 |
3-Hydroxybenz(a)anthracene |
127 |
L0193 |
| 28 |
Benz(a)anthracene-trans-3,4-dihydrodiol |
128 |
L0187 |
| 29 |
Benz(a)anthracene-trans-3,4-dihydrodiol-1,2-epoxide (anti) |
129 |
L0189 |
| 30 |
Benz(a)anthracene-trans-8,9-dihydrodiol-10,11-epoxide (syn) |
130 |
L0155 |
| 31 |
Benz[a]anthracene-trans-8,9-dihydrodiol-10,11-epoxide (anti) |
131 |
L0154 |
| 32 |
7,12-Dimethylbenz(a)anthracene-trans-3,4-dihydrodiol |
132 |
L0751 |
| 33 |
Dibenzo[a,l]pyrene |
133 |
G0479 |
| 34 |
(+/-)-r-11,t-12-Dihydroxy-t-13,14-epoxy-11,12,13,14-tetrahydrodibenzo[a,l]pyrene (anti) |
134 |
L0980 |
| 35 |
Chrysene-trans-1,2-dihydrodiol-3,4-epoxide (anti) |
135 |
L0500 |
| 36 |
Chrysene-trans-1,2-dihydrodiol-3,4-epoxide (syn) |
136 |
L0512 |
| 37 |
3-Hydroxychrysene |
137 |
L0413 |
| 38 |
1-Hydroxychrysene |
138 |
L0460 |
| 39 |
Benzo[c]phenanthrene-3,4-diol-1,2-epoxide |
139 |
L0983 |
| 40 |
1-Hydroxybenzo[c]phenanthrene |
140 |
L1106 |
| 41 |
Benzo[g]chrysene-11,12-diol-13,14-epoxide (anti) |
141 |
M1013 |
| 42 |
1-Pyrenyl-B-D-Glucopyranosiduronic acid |
142 |
K1103 |
| 43 |
1-Hydroxypyrene |
143 |
L0723 |
| 44 |
Dibenz(a,c)anthracene-trans-10,11-dihydrodiol-12,13-epoxide (anti) |
144 |
L0456 |
| 45 |
(+/-)-anti-7,12-Dimethylbenz[a]anthracene-3,4-dihydrodiol-1,2-epoxide |
145 |
L1313 |
|
| 46 |
(+/-)-syn-7,12-Dimethylbenz[a]anthracene-3,4-dihydrodiol-1,2-epoxide |
146 |
L1312 |
|
| 47 |
1,2-Dihydroxy-3,4-epoxy-1,2,3,4-tetrahydrophenanthrene (anti) |
147 |
L1317 |
|
| 48 |
5-Methylchrysene |
148 |
M0866 |
| 49 |
5-Methylchrysene-r-1,t-2,3,c-4-tetrahydrotetrol |
149 |
L0870 |
| 50 |
Cyclopenta[c,d]pyrene |
150 |
J0471 |
| 51 |
Dibenzo[a,i]pyrene (Benzo[rst]pentaphene) |
151 |
G0062 |
| 52 |
Benzo(k)fluoranthene-trans-8,9-dihydrodiol-10,11-epoxide (anti) |
152 |
L0746 |
|
| 53 |
Benzo(b)fluoranthene-trans-9,10-dihydrodiol-11,12-epoxide (anti) |
153 |
L0798 |
|
| 54 |
N-Nitrosomethylurea (NMU) |
201 |
E0049 |
| 55 |
N-Methylacetoxymethylnitrosamine |
202 |
E0215 |
| 56 |
N-Nitroso-L-proline |
203 |
E0174 |
| 57 |
N-Nitrosonornicotine (NNN) |
204 |
E0151 |
| 58 |
N-Methylbenzylnitrosamine |
205 |
E0089 |
| 59 |
4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) |
206 |
E0698 |
| 60 |
N-Nitrosoanabasine |
207 |
E0840 |
| 61 |
N-Nitrosoanatabine |
208 |
E0831 |
| 62 |
4-(N-Methyl-nitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) |
209 |
E1154 |
| 63 |
N-Nitrosoguvacoline |
210 |
E1061 |
| 64 |
N-Acetoxy-2-acetylaminofluorene |
301 |
AM0030 |
| 65 |
Azoxymethane |
302 |
F0044 |
| 66 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) |
303 |
D0440 |
| 67 |
Methylazoxy methanol acetate |
304 |
F0040 |
| 68 |
7H-Dibenzo(c,g)carbazole |
305 |
H0258 |
| 69 |
2-Hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-Hydroxy PhIP) |
306 |
L1096 |
|
| 70 |
Cholanthrene |
307 |
G0502 |
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