Analytical Chemist for Exposomics/Metabolomics

Thomas Spratt

The Turesky laboratory at the Masonic Cancer Center, University of Minnesota, Minneapolis, is recruiting a Ph. D. scientist  (Post-Doctoral Associate, or Research 5) to conduct biomarker research programs for human risk assessment of environmental and dietary toxicants on NIH funded programs in the Turesky laboratory.

About the Job:

An experienced analytical mass spectrometrist is sought to develop and validate biomarkers of exposures to environmental and dietary carcinogens, their metabolites and DNA adducts in cells, urine, and human tissues. The research requires hands-on experience in LC/MS and mass spectrometric characterization of biomarkers in complex biological matrices. A candidate with a background in metabolomics or exposomics research is highly desirable. The candidate is expected to work semi-independently in LC/MS development and validation of DNA adduct biomarkers or metabolomics/exposomics employing triple quadrupole, ion trap and high-resolution MS instruments. The Research 5 candidate is expected to aid in multiple projects and maintaining the laboratories LC and MS instruments.

Qualifications:

  • Doctoral Degree-required, preferred field of study in analytical science, biology, biochemistry, chemistry, or related field for (Post-Doctoral Associate)
  • Doctoral Degree-required, preferred field of study in analytical science, biology, biochemistry, chemistry, or related field with two years of research experience post PhD degree for (Research 5)
  • Extensive hands-on experience on operating and maintaining LC mass spec instruments (triple quadrupole, ion trap MS, or high resolution Orbitrap mass spectrometry) and data analysis software
  • The candidate should have conducted qualitative or quantitative analysis of biomarkers, trace-level analysis of biomolecules in biological matrices.
  •  Excellent written and oral communication skills.
  • The candidate must be organized and work diligently to meet timelines.

Preferred qualifications

  • Prior research in exposomics or metabolomics
  • Strong computer skills and experience in post-data analysis of metabolomics data and biostatistics

About the Lab:

Our research is focused on the biochemical toxicology of dietary and environmental genotoxicants, as well as endogenous electrophiles that damage protein and DNA. Our long-term objectives are to understand the roles of chemicals in cancer etiology and other diseases through mechanistic studies. We implement chemical markers and state-of-the-art mass spectrometry methods for use in molecular epidemiology studies that seek to understand the origin of human cancer for which an environmental cause is suspected.

Please contact Dr. Robert Turesky for further information (email: Rturesky@umn.edu)

posted May 17, 2021