TOXI Award Winners

TOXI Award Winners

Oral Presentation Awards

  • Susanne Geisen (graduate student, ETH), Nora Escher, Claudia M. Aloisi, Shana Sturla Chemical mechanism of O6-carboxymethyldeoxyguanine formation from azaserine and abundance in cells
  • Katherine Hurley (postdoc, ETH), Jasmin Zgraggen, Tania Cruz, Alejandro Ramirez-Garcia, Clarissa Schwab, Shana Sturla Biosynthesis of acrolein with a coupled enzyme system to emulate continuous acrolein production by gut microbiota
  • John Terrell (graduate student, Vanderbilt), Francesca Gruppi, Robert J. Turesky, Carmelo J. Rizzo Covalent binding of anthracyclines to AP sites in DNA suggest an unstudied mechanism of cytotoxicity from chemotherapeutic regimens
  • Junzhou Wu (postdoc, MIT), Peter C. Dedon Derivatization of Phosphorothioate DNA modifications by direct chemical conjugation

Poster Presentation Awards

  • Kiara Fairman (postdoc, FDA), Annie Lumen Contribution of parameter sensitivities to the predictive potential of pregnancy-induced pharmacokinetic changes for antihypertensives using physiologically based pharmacokinetic (PBPK) modeling
  • Caitlin C. Jokipii Krueger (graduate student, Minnesota), Dominic Najjar, Xiaotong Lu, Natalia Y. Tretyakova Endogenous versus exogenous sources of N7-(2,3,4-trihydroxybut-1-yl) guanine and N7-(1-hydroxyl-3-buten-1-yl) guanine DNA adducts
  • Alessia Stornetta (postdoc, Minnesota), Peter W. Villalta, Erik S. Carlson, Emily P. Balskus, Silvia Balbo Analysis of double-stranded oligodeoxynucleotides crosslinked by the bacterial genotoxin colibactin using HILIC chromatography and high-resolution mass spectrometry
  • Jingjing Sun (postdoc, ETH), Nicole M. Antczak, Shana J. Sturla Molecular beacon reporters of substrate specificity of DNA 8-oxoguanine glycosylase mutants