Newsletter October 2021

Message from Chair
TOXI Program at ACS Meeting
TOXI Awards
Engage young scientists
Publishing workshop
Thanks to our Sponsors
Election
Jobs

Message from Chair

Greetings to all TOXI members! I was able to attend the Fall ACS meeting In Atlanta in person. The meeting was conducted in a hybrid format, with the majority of participants joining online. I was very grateful for the opportunity to interact with other participants during the conference, to share a meal with symposia speakers at a local restaurant, and to personally present John Essigmann with the Founders Award. The meeting was definitely a success! I especially enjoyed the poster session on Tuesday morning on Gather (gather.town) and the panel discussions. Please read on for a report of the program and recognition of 2021 TOXI award winners. My special congratulations to the graduate and postdoc awardees whose scientific accomplishments and career development are a major driver for the Division.

Please make sure to participate in the 2021 TOXI elections. The nominees for positions opening on the TOXI executive committee are listed below. All members are urged to cast their votes. I would like to personally thank the nominees who have agreed to contribute their time and energy to support the Division. Any TOXI members interested in becoming involved in the leadership and organization of the division are encouraged to reach out to members of the Executive Committee directly at any time.

TOXI Program at the ACS Meeting

 ACS Fall 2021 Atlanta and online hybrid National Meeting Program; August 22-26

The TOXI division celebrated the 25th anniversary of its founding in 2021 with a hybrid in-person and online meeting program. The meeting was held Sunday-Wednesday with scientific sessions, professional development opportunities and division business meetings. Posters and talks were presented live, and many recorded presentations were also available during and after the meeting. The Program Committee and the TOXI division thank NIEHS, Chemical Research in Toxicology, Thermo Fisher Scientific, Bristol Myers Squibb, ACS, TOXI members, and Frederick and Susan Beland for generous funding of our program. Sunday and Monday featured both in-person and online content, following public health recommendations.

The meeting kicked off on Sunday with two award symposia. Congratulations to Prof. Christie Sayes at Baylor University for the Chemical Research in Toxicology Young Investigator Award for her work on toxicology along the supply chain, with a focus on nanomaterial toxicity. She organized an exciting symposium that included Robert Strongin, Portland State University, who spoke about potential environmental exposures due to vaping products. Sherine Obare, University of North Carolina, Greensboro, spoke about her work on nanoparticle toxicity, while the work of April Gu’s laboratory at Cornell on drinking water disinfection byproducts was also presented.

Prof. John Essigmann from MIT was recognized with the TOXI Division Founders’ Award for his work on DNA damage and mutagenesis. Prof. Essigmann organized a symposium featuring an arc of work on the metabolism of DNA lesions in multiple cellular contexts. Also included in the symposium were Natalia Tretyakova (University of Minnesota), who discussed DNA-protein cross-links; Deyu Li (University of Rhode Island), who presented his work on identifying endogenously generated lesions that can be substrates for damage bypass DNA polymerases; Sarah Delaney (Brown University), who spoke about base excision repair in the context of chromatin; Shana Sturla (ETH-Zurich), who presented her work on genomic patterns of chemically induced DNA damage and mutagenesis.

The TOXI keynote address was given by Patrick Breysse from the Centers for Disease Control, who gave an insightful and wide-ranging presentation featuring several different examples of how biological monitoring can inform public health and regulatory decision-making.

Michael Trakselis, Baylor University, and Laura Niedernhofer, University of Minnesota, organized a session on Toxicants and Cellular Aging co-sponsored with the BIOL division. Michael Trakselis presented his group’s work on the involvement of the MCM8/9 recombination helicase in stabilizing stalled replication forks and regulating fork progression. Non-B-DNA forms H-DNA and Z-DNA contribute to mutagenesis due to their enrichment near translocation regions, as discussed by Karen Vasquez, University of Texas, Austin. Patricia Opresko, University of Pittsburgh, presented a tool developed by her laboratory to induce oxidative stress and generate 8-oxo-dG only in telomeres in order to probe the mechanisms by which chronic 8-oxo-dG leads to telomere fragility and loss, triggering senescence. Weiwei Dang, Baylor College of Medicine, addressed the effects of histone levels and modifications in yeast lifespan. Finally, Laura Niedernhofer reported on her work showing that senescent cells play a causal role in aging and age-related diseases.


An in-person poster session was held in Atlanta Sunday evening, complemented by an online poster session on Tuesday. Posters were also available throughout the meeting with short recorded presentations.

Monday morning featured the Student and Postdoctoral Scholar Symposium, organized by Erin Prestwich and Ujjal Sarker. Some highlights include Merve Demir’s, University of California, Davis, identification of a MutY loop that is important for 8-oxo-dG recognition, and Taylor Dodson’s, University of Toledo, work showing the changed in tRNA modifications due to diabetes.

The TOXI anniversary sticker was designed by Caroline Germeaux.
The TOXI anniversary sticker was designed by Caroline Germeaux

The 25th anniversary of the TOXI division was celebrated with a symposium organized by Michael Trakselis and Sarah Shuck, City of Hope, featuring former and current TOXI division leaders Fred Guengerich, Vanderbilt University, Nicholas Geacintov, New York University, Lisa Peterson, University of Minnesota, Stephen Hecht, University of Minnesota, Shana Sturla, and Natalia Tretyakova. Michael Stone, Vanderbilt University, gave a historical overview of the early days of the division. The symposium highlighted the development of the division in parallel with the development of the different scientific fields of interest to the division.

Maureen McKeague
Maureen McKeague, McGill University, gave the Kavli Emerging Leader in Chemistry Keynote Lecture “Chemistry of DNA Damage and Measuring Genomic Resilience.”

Thinking Outside the Well: Novel Assays in Drug Discovery & Development was organized by Donna Huryn, University of Pittsburgh, and Michael Walters, University of Minnesota and co-sponsored with the MEDI division. Donna Huryn described a zebrafish model system for screening compounds active in treating acute kidney injury, a disease common in those spending time in the ICU and for which there are no prognostic biomarkers. Randall Peterson, University of Utah, described another zebrafish screen, in this case identifying chemicals that disrupt social behavior in fish to identify autism-related genes. Thalita Boldrin Zanoni, Charles River Laboratories; Banupriya Sridharan, GlaxoSmithKline, and Marc Ferrer, National Institutes of Health, discussed cell and tissue models that can reduce the need for animal models in research and development.

TOXI hosted a live poster session Tuesday morning on Gather (gather.town), which allowed participants to browse posters and interact with participants mimicking an in-person poster session.

The Topics in Chemical Toxicology symposium was organized by Sarah Shuck and Linlin Zhao.  Shilpi Paul, Pennsylvania State University Hershey described work to determine proteins associated with damage-bypass polymerase pol kappa in human cells. Kari Knobbe, University of Missouri, reported the development of a model describing steroid metabolism by cytochrome P450 in stress responses. The excellent presentations in this session covered a range of topics including, a range of methods to detect and characterize toxicants and their metabolites in cells, repair of DNA adducts, and their cytotoxicity.

Harnessing the Microbiome for Disease Prevention & Therapy, organized by Nick Meanwell, Bristol Myers Squibb, and Fred Guengerich, featured James Brown, Kaleido Biosciences; Jingwei Cai, Genentech; Jason Crawford, Yale University; and Beth McCormick, University of Massachusetts Medical School. Presentations covered a range of topics related to host-microbe interactions and the impact of the metabolism of each on drug discovery.

The TOXI programming wrapped up on Wednesday with a Publishing workshop, led by Chemical Research in Toxicology editors and the TOXI business meeting. An excellent conclusion to the meeting was the Career Mentoring Panel Discussion organized by Sarah Shuck and featuring Amanda Bryant-Friedrich (Wayne State University), Kirsten Fertuck (Northeastern University), and Jason Walsh (Pfizer). Participants benefitted from the insightful discussion on identifying mentors, the value of multiple mentors, seeking and using career advice, and many more topics.

TOXI Award Winners

 Oral Presentation Awards

Kari Knobbe (undergraduate, University of Missouri), Joseph Schell, Rainer Glaser “Your Body’s Response to Stress: The Enzymatic Oxidation of Deoxycorticosterone by Cytochrome P450 CYP11B2”

Samuel Herndon (undergraduate, Wright State University), Praveen Kumar Alla, Kelsey Hood, Norma Adragna, Ioana Pavel “Developing GFAAS- and ICP-OES-based methodologies for studying the toxicity and interactions of silver nanoparticles with human red blood cells”

Nikolai Püllen (graduate student, ETH), Hailey Gahlon, Shana Sturla “Removal of common alterations in genomic DNA for accurate damage sequencing”

Dominique Gaffney (graduate student, University of Arizona), Erin Jennings, Marissa Trujillo, Micaela Roy, Julie Reisz, Diego Perez-Gamboa, Emely Hoffman, David Orlicky, James Wepy, Brenda Crews, Angelo D’Alessandro, Lawrence Marnett, James Galligan “Methylglyoxal derived post-translational modifications restore metabolic homeostasis in diet induced metabolic disorder”

Taylor Dodson (graduate student, University of Toledo), Chao Liu, Samuel Senyo, Erin Prestwich “Analysis of post-transcriptional modifications in tRNAs associated with hyperglycemia in diabetes-associated cells”

Shane Byrne (postdoc, MIT), Yifeng Yuan, Michael DeMott, Stefanie Kellner, Bo Cao, Eric Alm, Peter Dedon “Uncovering the landscape of phosphorothioates in the human gut microbiome”

Shilpi Paul (research fellow, Penn State University), Paolo Cifani, Darryl Pappin, Thomas Spratt “Exploring the interactome of translesion DNA synthesis polymerase kappa”

Poster Presentation Awards

Mansi Kinare (undergraduate, Northeastern University), Lakindu Pathira Kankanamge, Penny Beuning, Mary Ondrechen “Analysis of Interactions of Human Polymerase Kappa and DinB Polymerases with Damaged DNA”

Eric Carlson (graduate student, University of Toledo) Taylor Dodson, Chase Morse, Nathan Wamer, Erin Prestwich “Characterization of phenotypic and DNA modifications of Pseudomonas aeruginosa wild-type and genomic variant strains:

Joseph Kaszubowski (graduate student, Baylor University), Michael Trakselis “Beyond the lesion: The switch-back to high fidelity synthesis”

Caitlin Jokipii Krueger (graduate student, University of Minnesota), Erik Moran, Natalia Tretyakova “Endogenous versus exogenous sources of monohydroxy-3-butenyl and dihydroxybutyl mercapturic acid metabolites and N7-(1-hydroxy-3-buten-2-yl) guanine DNA adducts”

Arnold Groehler (postdoc, Institute for Basic Science, Ulsan, Korea), Anuar Makhmut, Nhat Mai Dao, Orlando Schärer “Monitoring the formation and repair kinetics of cisplatin-induced DNA-DNA cross-links by comprehensive ultra-performance liquid chromatograph-selective ion monitoring (UPLC-SIM)”

Katherine Hurley (postdoc, ETH-Zurich), Jasmin Zgraggen, Tania Cruz, Sabine Diedrich, Xuan Li, Shana Sturla “Biosynthesis of acrolein with a coupled enzyme system to emulate continuous acrolein production by gut microbiota”

Engaging Early-Career TOXI Scientists

To encourage the participation of early-career TOXI scientists and to disseminate the TOXI program more widely, Dr. Michael Trakselis again recruited TOXI trainees to write up synapses and perspectives on Programmatic Sessions this year. These student authors were awarded ACS registration scholarships. Three ToxWatch articles and one letter to the Editor are being prepared for submission to Chemical Research in Toxicology, along with an editorial to be published in October. Keep an eye out for these articles to be published in the coming months!

Publishing Workshop

Chemical Research in Toxicology conducted a Publishing Workshop at the ACS Meeting.

Here are the slides for download: https://www.acschemtox.org/publishing-workshop-slides/

Thanks to Our Sponsors

The Division of Chemical Toxicology thanks the sponsors who have provided funds for our Program at the American Chemical Society National Meeting in Atlanta GA.


Fred and Susan Beland


The 2021 Election

The 2020 election will begin towards the end of October. Current TOXI members will receive their election credentials via email.
The nomination will remain open to all active TOXI members. If you have a colleague or yourself to nominate, please send your photo and a short biosketch to Linlin.Zhao@ucr.edu

Secretary

The Secretary is responsible for communications between Executive Committee and TOXI members as well as the ACS.  The Secretary takes the minutes at the Executive Committee Meetings and keeps Divisional documents organized.  The Secretary notifies the Nominations Committee Chair of the vacancies for the next election and then conducts the election. 

Linlin Zhao

Assistant Professor in the Department of Chemistry at the University of California, Riverside. He received his B.S. degree in Chemistry from Jilin University in China (2005) and Ph.D. degree in Bioanalytical Chemistry from University of Connecticut (2010) under the supervision of Profs. James Rusling and John Schenkman. He worked with Prof. F. Peter Guengerich at the Department of Biochemistry at Vanderbilt University School of Medicine as a postdoctoral fellow focusing on the enzymology of specialized DNA polymerases in the context of mutagenicity of carcinogen-modified DNA. He started his independent career in the Department of Chemistry and Biochemistry at Central Michigan University in 2013, and relocated to the Department of Chemistry at University of California, Riverside in 2019.

His research program centers on the mechanistic enzymology of DNA replication and repair and chemical biology of DNA modifications. His on-going research focuses on elucidating the chemical and molecular mechanism of mitochondrial DNA degradation and developing novel techniques to map DNA modifications at nucleotide resolution. He has published 14 peer-reviewed papers as an independent investigator and 32 in total in his career. His research has been supported by extramural grants from National Institutes of Health and Department of Defense. Dr. Zhao was the recipient of the 2017 Provost’s Award in research, a top research honor for young faculty at Central Michigan University (given to only two faculty per year). He has been an active member of ACS TOXI division since he was a graduate student. He has been actively involved in organizing and presiding the session and judging the oral and poster presentations in the past TOXI meetings. He has been a member of the Program Development Committee since 2017. Currently, he is the Secretary of the Division (2020-2021) and look forward to serving a second term!

Deyu Li

Associate Professor in the College of Pharmacy at the University of Rhode Island.  He received Ph.D. in organic chemistry from Brown University (2009) under the supervision of Prof. Paul G. Williard. Then he worked with Prof. John M. Essigmann in the Departments of Chemistry and Biological Engineering at the Massachusetts Institute of Technology as a postdoctoral associate focusing on the AlkB family DNA repair enzymes and antiviral drug development. In July 2014, he started his laboratory in the College of Pharmacy at the University of Rhode Island.  His research has focused on developing chemical and biological methods to solve medical and environmental problems. His work focuses on DNA adducts generated from different exogenous and endogenous chemicals and study their mutational patterns and repair pathways. Dr. Li has published 13 peer-reviewed papers at URI and 46 in total in his career. His research has been supported by the Outstanding New Environmental Scientist (ONES) Award (RO1) and an R15 award from NIH. Currently he is the Paramaz Avedisian Endowed Chair in Medicinal Organic Chemistry. He was awarded the Early Career Faculty Research & Scholarship Excellence Award by URI.  He was also selected as a faculty inductee of The Kappa Psi Pharmaceutical Fraternity and The Rho Chi Society.  He has been a member of the American Chemical Society since 2002. He has been actively participating the activities in the Division of Chemical Toxicology and is a member of the Communications Committee. His work includes regularly updating the Facebook page of the Division and posting papers published in Chemical Research in Toxicology.

Treasurer-Elect

The Treasurer and Treasurer-Elect shall each serve two-year terms. The Treasurer-Elect shall accede to the office of Treasurer at the end of the term of office. The Treasurer shall have charge of the funds of the Division and shall receive payments and make all disbursements subject to the approval of the Executive Committee. A report of the Treasurer shall be submitted to the Division at its annual meeting. The financial portion of this report shall be audited by a qualified external auditor. The Treasurer-Elect shall fulfill the duties of the Treasurer in the absence of the Treasurer.

Grover P Miller

Professor in the Dept of Biochemistry and Molecular Biology at Univ of Ark for Medical Sciences. He teaches medical, graduate, and undergraduate students about protein chemistry, enzymology, xenobiotic metabolism, and scientific communication and maintains an active research program. Prof. Miller’s group leverages powerful analytical, biochemical and computational tools to identify and quantitate small molecules including drugs, dietary molecules, and pollutants during metabolism and correlate findings to biological activity and in vivo outcomes such as liver toxicity. His career began earning Chemistry and Biochemistry BS degrees from Louisiana State Univ (1992) and then a PhD under Stephen J. Benkovic from Penn State Univ (1997). He pursued postdoctoral research under F. Peter Guengerich at Vanderbilt Univ and earned an NIH NRSA Award. In 2001, he joined the Univ of Ark for Medical Sciences to set up his own research program.

During his research career, he delivered 37 invited lectures, published 60 peer-reviewed manuscripts and 12 reviews, and authored 2 US patents. He serves on 3 editorial boards – Drug Metab Dispos, Drug Metab Rev, and Metabolites. His efforts have been further recognized with roles as Chair (4) and Reviewer (32) on regional, national and international research study sections. That service includes stints as ad hoc and standing member of the NIH Xenobiotic and Nutrient Disposition and Action [XNDA] Study Section (2018 to present). For the ACS, he chaired sessions at Regional (2008/21) and Natl ACS meetings (2014). Locally, he served as ACS Section Secretary (2011-12), Chair-Elect (2013), and Chair (2014-15) as well as Chair of Revision of Bylaws (2011-12), Program (2013-14), Recruitment (2013-15), and Public Relations (2016-17) Committees. For the 74th Annual Southwest Regional Meeting of the ACS, he co-Chaired Organizing, Program, and Public Relations Committees, respectively, (2014-2018). During those years, he received 2 Outstanding ACS Service Awards (2011-2012). Lastly, for the ACS TOXI Division, Prof. Miller served as an Alternate Council (2017-2019) and member of the Program Development Committee (2017-2021) as well as organized the first regional TOXI session at the 74th Annual Southwest Regional Meeting of the ACS (2018).

Member-at-Large

 Members-at-Large to the Executive serve three year terms. The role of this position is two-fold: to help the Chair run the division by providing advise and chairing standing committees, and to learn how the Division is run in order to be an effective future Division Officer.

Stacy G. Wendell

Associate Professor in the Department of Pharmacology and Chemical Biology at the University of Pittsburgh.  She completed her requirements for BS degrees in both Biochemistry and Biology at Mount Saint Mary’s University in Emmitsburg, MD and a PhD in Chemistry from the University of Maryland Baltimore County. Her dissertation research investigated multiple chromatographic techniques used for the discrete separation of modified oligonucleotides. After graduate school Dr. Wendell was a postdoctoral fellow at the University of Pennsylvania where she elucidated the molecular mechanisms of environmental causes of lung cancer. Under the mentorship of Dr. Ian Blair and Dr. Trevor Penning, she obtained an NRSA F32 from NIEHS focused on the mechanisms of benzo[a]pyrene (B[a]P) transport and metabolism. She also helped to define contributions of the CYP and aldoketo-reductase metabolism pathways to B[a]P-mediated lung carcinogenesis.  Secondary projects focused on the formation and signaling of arachidonic-acid derived bioactive fatty acids and their role in the lung. During her time at Penn Dr. Wendell became an expert in LC-MS method development for small molecules and lipids using atmospheric ionization techniques. These important studies are the foundation for her University of Pittsburgh research program focused on the application of mass spectrometry in the formation and signaling of bioactive fatty acids and their role in asthma and immune cell modulation.

Throughout her training and career Dr. Wendell has been dedicated to the professional development and mentoring of trainees. During her postdoc training, Dr. Wendell was the chair of the Biomedical Postdoc Association at Penn and transitioned into chairing the board of directors for the National Postdoctoral Association, a 501(c)3 organization. As faculty she has continued mentoring trainees at all levels, within her laboratory and as the Scientific Director for the Health Sciences Metabolomics and Lipidomics Core. Recent trainees include a PhD student, medical student in the physician scientist training program and an MD/PhD student, all who have received training grants under Dr. Wendell’s mentorship. She is deeply committed to the scientific and professional growth of all trainees and readily encourages the development of transferable skills and the exploration of career paths through career coaching and through the more formalized course offered in her home department, “Foundations of Successful Career Planning and Development”. Currently, Dr. Wendell is a member of the Society for Free Radical Biology and Medicine Women in Science Committee, and has been a longstanding member of the ACS Division of Chemical Toxicology.  Although she had taken a step back from formal committee involvement to build up her lab and start a family, Dr. Wendell is ready to engage in and promote the scientific and professional activities supported by the Chem Tox division.

Christie M. Sayes

Practicing research scientist in the fields of toxicology, chemistry, material science, and environmental health. Currently, she holds the position of Associate Professor of Environmental Science & Toxicology at Baylor University (Waco, Texas). Sayes is a subject matter expert in advanced materials, human exposure & health effects and risk science. Her activities include working with partners, collaborators, and trainees in designing studies related to safety-by-design considerations of engineered materials used in drug delivery and consumer product applications.  Sayes is also interested in occupational safety and environmental transformations of particle systems in complex matrices.  She possesses a working knowledge of laboratory science and U.S. regulatory climates. Routine activities include cell culture, zebrafish and rat in vivo models, biomolecular mechanistic analyses, mass spectrometry, electron microscopy, and statistics.  Data sets are always related back to the published literature, compared against appropriate controls, and verified using orthogonal methods.

Sayes was formerly a Director of Environmental Health of Advanced Materials at RTI International (Durham, NC), Adjunct Professor of Nanoscience within the University of North Carolina System, and an Assistant Professor of Toxicology at Texas A&M University (College Station, TX).  She has two decades of experience in the fields of nanotechnology, nanomedicine, and nanotoxicology and has authored more than 150 publications, including original research, invited reviews, and book chapters. She is a member of the Society of Toxicology (SOT), American Chemical Society (ACS), Society for Risk Analysis (SRA), and was recently awarded membership into the Royal Society of Chemistry (RSC) for her contributions in the field of particle toxicology. She also serves as an Associate Editor for the Oxford University Press Toxicology Research and on the Editorial Board of the journals Toxicological Sciences and Nanotoxicology. As an active member of SOT, Sayes is the Past-President of North Carolina Regional Chapter, the Past-President of Lone State Regional Chapter, and President-Elect of the Nanoscience & Advanced Materials Specialty Section.  For SRA, she served as the Co-Chair of the Advanced Materials and Technology Specialty Group.  For ACS, she served as the Fall Program Chair for Environmental Chemistry Division.  Sayes serves on the organizing committee for the International Advisory Board for the Nanotoxicology (bi-annual) Conference.

Christie received her Ph.D. in Chemistry in 2005 from Rice University (Houston, TX).  Her dissertation focused on the ‘nano-bio interface’. After graduation, she joined The DuPont Company as Visiting Scientist and aided in the development of the DuPont-Environmental Defense Nano Risk Framework – the international standard for assessing risks associated with engineered nanomaterials.

Member of the Nomination Committee

The Nominating Committee consists of three members, one elected each year. The member with the longest tenure on the committee shall serve as Chair. Each year the Secretary of the Division contacts the members of the Nominating Committee and stipulates the offices that are to be filled. In making the nominations, the committee should be attentive to issues of diversity and look for broad representation within the membership of the division. The nominations should be submitted to the Executive Committee at their meeting, which falls during the national ACS meeting. At the business meeting of the general membership, the Chair should open the floor for additional nominations. Once the nominations are closed, the Secretary should be informed as to the nominees and prepare the ballots accordingly.

Thomas Spratt

Professor of Biochemistry and Molecular Biology at the Penn State College of Medicine in Hershey PA.  Tom received a BA in Chemistry from the University of Rochester and a PhD in bioorganic chemistry from the University of Chicago.  He did post-doctoral research with Heinz Floss at the Department of Chemistry at Ohio State studying mechanisms of DNA alkylation using chiral methyl alkylating agents. He went on to study with Steve Hecht at the American Health Foundation where he was introduced to tobacco carcinogenesis. His research at the American Health Foundation and Penn State has focused on mechanisms of DNA repair, fidelity of DNA polymerases and how carcinogen-induced mutations occur. Tom has been an active member of the Division of Chemical Toxicology, American Chemical Society since its inception, serving as a member of the Awards Committee (2009-2012), Secretary (2008-2011), Program Chair (2016-2019), and Chair of the Publicity/Communications Committee (2007-present). Tom has been an active member of joined TOXI at its inception. He organized two symposia for the Division, was Secretary of the Division for four years, Program Chair for three years, and has lead the TOXI Publicity Committee for the past 13 years. He has also served on the Advisory Board for Chemical Research in Toxicology (2004-2007, 2018-present).

Shana Sturla

Professor of Toxicology at the ETH Zurich, Switzerland. Prof. Sturla was born in Brooklyn, New York and studied Chemistry at the University of California at Berkeley and the Massachusetts Institute of Technology. She was a postdoctoral fellow at the University of Minnesota Cancer Center with Prof. Stephen Hecht. Goals of her research are to elucidate the chemical basis of mutagenesis and toxicity, and to promote innovative bioanalysis strategies for predicting chemical hazards and precision responses to cancer therapeutics. Prof. Sturla teaches courses in Toxicology, Chemical Biology and Carcinogenesis. She is the immediate past chair of the Division, Vice President of the Swiss Society of Toxicology, Member of the Swiss Academies of Science Platform Chemistry, and Editor-In-Chief of Chemical Research in Toxicology. Shana enjoys biking, running, cross country skiing, rowing and learning curious functionalities in ChemDraw from her 8-year old son. www.toxicology.ethz.ch @ProfessorShana @Toxicology_ETH

Job Postings

Postdoctoral Positions in Clinical DNA Adductomics Peter Dedon’s group at MIT.  Job Posting

Postdoc Position in Structural and Functional Characterization of Macromolecular Complexes in Transcription and Repair Dong Wang Lab at University of California, San Diego.  Job Posting

Tenure Track Faculty Position – Toxicological Chemist Job Posting