June 2020 Newsletter

June 2020 Newsletter

Message from Chair
Keynote Lecture: Cindy Burrows
Founders’ Award: Peter Dedon
Chemical Research in Toxicology Young Investigator: Elijah Peterson
TOXI Twitter-Sphere
Nominations for TOXI Executive Committee
TOXI National ACS Meeting Program
TOXI Future National ACS meeting program


Message from Chair

I hope all members of our TOXI community, and friends and family are safe and healthy in these extraordinary times.  The location for our fall meeting has been moved from San Francisco to the World Wide Web: https://www.acs.org/content/acs/en/meetings/national-meeting.html 

We are committed to offer an excellent virtual version of our annual gathering and in the coming weeks we will be coordinating a combination of live and on demand options to share content and create opportunities for meaningful interaction online.

We are pleased to share this month’s newsletter with a focus on highlighting the amazing achievements of our 2020 keynote speaker, Cindy Burrows, and congratulations to Pete Dedon, winner of the Founders’ Award, and to Elijah Peterson, the 2020 CRT Young Investigator. We also highlight online engagement efforts of our TOXI publicity committee and invite nominations for open TOXI positions.

Penny Beuning has lead a team that has created a wonderful program. A summary of the program is below. You can find the program and abstracts at this link :  Full Program and abstracts.

 

Shana Sturla
ETH Zurich
Chair, Division of Chemical Toxicology


Keynote Speaker.  Cindy Burrows

by Samuel Howarth, University of Rhode Island

Cindy Burrows

Dr. Cynthia J. Burrows is selected as the 2020 ACS Chemical Toxicology Division keynote speaker.. Dr. Burrows is currently a Distinguished Professor of Chemistry at the University of Utah, in addition to the Thatcher Presidential Endowed Chair of Biological Chemistry.  Dr. Burrows has authored over 200 publications, as well as a multitude of book chapters, editorials, and patent applications. One aspect of her current research investigates the relationship between oxidative nucleic acid modifications, epigenetics, and cancer. Dr. Burrows has also worked to develop nanopore sequencing technology capable of detecting various forms of DNA or RNA damage.  Visit her lab website

In 2019, Dr. Burrows was awarded the University of Utah’s Rosenblatt Prize for going above and beyond what was expected of teacher, researcher, and administrator; this is the university’s highest faculty accolade. Furthermore, her dedication to improving education and expanding the scientific community at the University of Utah have earned her the Robert W. Parry Teaching Award, the University Distinguished Teaching Award, the Linda K. Amos Award for Distinguished Service to Women, and more. Dr. Burrows has also served on a number of editorial boards and review panels. Currently, she serves as the Editor-in-Chief of Accounts of Chemical Research, and in 2019 she received the ACS Editors’ Leadership Award.  In 2009, Dr. Burrows was inducted into the American Academy of Arts and Sciences and she was elected to the National Academy of Sciences in 2014.


Founders’ Award: Peter Dedon

Pete Dedon is the 2020 winner of the Division of Chemical Toxicology Founders’ Award.

The award was established in honor of the founders of the Division of Chemical Toxicology and recognizes scientists whose work exemplifies the founders’ vision of excellence in the field of chemical toxicology. Awardees are  members of the Division of Chemical Toxicology whose scientific activities have emphasized innovative research in the general field of chemical toxicology.  The winner is chosen by a committee currently chaired by Kent Gates

Pete Dedon
Founders’ Award

Past winners include:

2008   Lawrence J  Marnett
2009:  Stephen S Hecht
2010   Richard Loeppky
2011   F. Peter Guengerich
2012:  Thomas Baillie
2013:  Steve Tannenbaum
2014:  Paul Hollenberg
2015:  Arthur Grollman
2016:  Nicholas Geacintov and Suse Broyde
2017:  Ian Blair
2018:  Judy Bolton
2019: Trevor Penning

Pete is currently the Underwood-Prescott Professor in the Department of Biological Engineering at MIT, Lead Principal Investigator in the Singapore-MIT Alliance for Research and Technology Antimicrobial Drug Resistance Program (SMART), a founding member of the Chulabhorn Graduate Institute in Bangkok, and a member of the MIT Center for Environmental Health Science. His research group has developed a variety of analytical and informatic platforms for discovery science in epigenetics and epitranscriptomics in infectious disease and cancer. One platform coordinates comparative genomics, SMRT sequencing and mass spectrometry to discover novel epigenetic marks, such as the recent discovery of phosphorothioate and 7-deazaguanine modifications in bacterial and bacteriophage genomes in the human microbiome. In the realm of epitranscriptomics, his team has applied systems-level analytics to discover a mechanism of translational control of cell response in eukaryotes and bacteria involving site-specific reprogramming of tRNAs and an alternative genetic code.


Chemical Research in Toxicology Young Investigator: Elijah Peterson

The winner of the Chemical Research in Toxicology Young Investigator Award for 2020 is Elijah Peterson of the National Institute of Standards and Technology.  Elijah Peterson will lead a half-day conference session as part of the ACS Division of Chemical Toxicology program at the ACS Fall National Meeting in San Francisco, California.
Elijah graduated from Case Western Reserve University in 2003 with BS and MS degrees in Civil Engineering and a BA in Psychology. He received a PhD at the University of Michigan studying the uptake and elimination behaviors of carbon nanotubes using earthworms and sediment-dwelling oligochaetes. He then received a Fulbright scholarship to do postdoctoral research at the University of Joensuu in Finland where he studied the uptake and elimination of carbon nanotubes and fullerenes in Daphnia magna. Elijah joined NIST as a National Research Council postdoctoral research fellow from 2009-2010 and then became a staff research scientist in 2010.

His research involves developing robust standard methods for assessing the potential impacts of nanomaterials on organisms and humans.  He is studying how nanomaterials impact the standard battery of toxicological assays as well as developing new tests.  Thus, a research focus in his team is to identify potential artifacts and design control experiments and other modifications to those assays to minimize artifacts and misunderstandings. In addition, he is studying the use of NIST reference materials (RMs) as positive or negative controls for standard toxicity methods to improve assay reliability and generate reference data.

An example of his research is  the development of standard methods with C. elegans for use with nanomaterials and the application of advanced microscopy techniques to improve the robustness of the assays. The sources of variability for an ISO method for C. elegans growth inhibition are being evaluated through cause & effect analysis and experimentation to identify the most critical sources of variability in the assay. He is also focused on the development of methods to accurately quantify nanomaterial concentrations in environmental matrices and organisms to enable bioaccumulation protocols and provide number-based nanoparticle concentrations.

Previous winners of the award are:
2012:  Yinsheng Wang
2013:  Dean Naisbitt
2014:  Shana Sturla
2015:  Penny Beuning
2016:  Yimon Aye
2017:  Huiwang Ai
2018:  Simon Chan
2019: Silvia Balbo


Chemical Toxicology engagement on twitter!

Maureen McKeague
Maureen McKeague
Sarah Shuck
Sarah Shuck

Professors Sarah Shuck and Maureen McKeague have taken over the @acschemtox twitter feed.  You will have noticed a daily TOXI tweet, primarily on new publications.  If you’ve never seen our Tweets, look to the right. There it is, right on our website.

  • Please help us increase the engagement of our members and help recruit new Chemical Toxicology researchers.
  • If you have any relevant sources of news, info, events for us to tweet about, we would love to incorporate them into more regular tweets.
  • Also, please send us any news out of your own research groups (i.e. new student/researcher joined, new grant/award, new paper published, new instrument obtained).
  • Please also encourage your group meetings to join twitter, follow us, and retweet!

Call for Nominations.  TOXI Officers

Yinsheng Wang, Chair Nominations Committee

The nominations committee would like to call for nominations for the following positions in the Division that are up for elections:

  • Chair-Elect (2021-2022 term);
  • Member-at-large (2021-2023 term);
  • Nominations committee (2021-2023 term);
  • Councilor (2021-2023 term);
  • Alternative councilor (2021-2023 term).

Email Nominations Committee Chair Yinsheng Wang  at yinsheng@ucr.edu.

Members are also welcome to provide nominations at the Division’s business meeting, which usually takes place in the Fall ACS National Meeting.


TOXI National ACS meeting program

Program Chair, Penny Beuning, Northeastern University.

The Program is set.  Hopefully we will meet in San Francisco.  Below is a summary of our Program.  Full Program

Student and post-doc presentation award winners from 2019
Student and post-doc presentation award winners from 2019

 

Sunday Morning

TOXI Young Investigators Symposium

Organizers: Erin Prestwich and Ujjal Sarkar
Susanne Geisen, Yupeng Li, John Terrell, C. M. Sabbir Ahmed, Miao Li, Merve Demir, Katherine Hurley, Suresh Pujari, Matthew Cranford, Junzhou Wu

Sunday Afternoon

Founders Award

Organizer: Pete Dedon
Samie Jaffrey, Thomas Begley, Richard Gregory, Peter Dedon

Monday Morning

Toxicology of Antibody-Drug Conjugates

Organizers: Sanjeev Gangwar and Michael Trakselis
Carolyn Bertozzi, Peter Senter, Melissa Schutten, Willy Solis, Jagath Reddy

Monday Afternoon

Metabolism of Fluorinated Compounds and Safety Relevance

Organizers: Nicholas Meanwell, and Fred Guengerich
Nicholas Meanwell, Benjamin Johnson, Qiuwei Xu, Peter Jeschke

Tuesday Morning

Genome-wide Perspectives on the Formation, Repair, and Consequences of DNA Damage

Organizers: Sabrina Huber and Maureen McKeague
Aaron Fleming, Nikolai Püllen, Maureen McKeague, Sarah Delaney, John Essigmann, John Wyrick, Cécile Mingard

Tuesday Afternoon

Chemical Research in Toxicology Young Investigator Award Symposium

Organizer: Elijah Peterson
Menghang Xia, Monita Sharma, Vytas Reipa, Elijah Petersen

Tuesday Late Afternoon

Keynote Lecture.  Cindy Burrows

Organizer: Natalia Tretyakova

Tuesday Evening

Poster Session

Organizers: Penny Beuning and Erin Prestwich

Wednesday Morning

Chemical Exposures and Impact on Health

Organizers: Rob Turesky and Sarah Shuck
Kurt Pennell, Jamie DeWitt, Jon Sobus, Pamela Lein, David Balshaw, Robert Turesky

Wednesday Afternoon

Topics in Chemical Toxicology

Organizers: Linlin Zhao and Penny Beuning
Gunnar Boysen, Lisa Peterson, Michael Stone, Orlando Scharer, Nicholas Geacintov, Zucai Suo, Linlin Zhao, Vladimir Shafirovich, James Yan, Sunghwan Kim


TOXI Future National ACS meeting program

We invite you to suggest TOXI symposia for future ACS National Meetings. Note that programming occurs well in advance of the national meeting. Currently, we have three thematic sessions in place for the 2021 meeting (August 22 – 26, 2021, in Atlanta, GA). The fourth one is still to be decided.  Send in your proposals.

The symposium proposal form is at: http://www.acschemtox.org/news-and-events/ under Symposium Proposals.

Get involved and make sure TOXI programming is of wide interest!